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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOLC1
All Species:
15.76
Human Site:
S378
Identified Species:
26.67
UniProt:
Q14978
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14978
NP_004732.2
699
73603
S378
S
E
D
D
E
A
P
S
K
P
A
G
T
T
K
Chimpanzee
Pan troglodytes
XP_001171017
700
73581
S379
S
E
D
D
E
A
P
S
K
P
A
G
T
T
K
Rhesus Macaque
Macaca mulatta
XP_001112196
701
73703
S379
S
E
D
V
E
A
P
S
K
P
A
G
T
T
K
Dog
Lupus familis
XP_851848
704
74723
K385
S
E
D
E
A
P
A
K
P
A
G
T
T
K
N
Cat
Felis silvestris
Mouse
Mus musculus
O08784
1320
134983
S826
T
E
D
S
D
S
S
S
E
E
S
D
S
D
T
Rat
Rattus norvegicus
P41777
704
73545
K388
S
E
D
E
A
P
A
K
P
V
S
A
T
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511079
669
69188
S332
D
S
D
S
D
S
D
S
S
E
D
E
A
P
A
Chicken
Gallus gallus
XP_421630
694
72200
S361
E
K
G
G
S
K
L
S
T
K
Q
P
V
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689627
1001
102013
K583
S
S
S
D
E
E
P
K
K
K
P
A
T
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_730693
686
70584
A336
A
P
K
K
V
A
P
A
K
A
T
P
A
K
A
Honey Bee
Apis mellifera
XP_001120943
685
75016
K354
A
S
K
I
S
S
K
K
E
E
S
S
S
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796224
791
84162
D446
A
A
K
K
P
V
E
D
S
S
S
S
D
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001168628
517
55362
V211
S
G
E
T
T
E
T
V
K
E
D
D
H
K
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32583
406
40997
S100
E
S
S
S
E
S
D
S
S
S
S
G
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
94.2
81.5
N.A.
24.9
74.1
N.A.
50.7
43.6
N.A.
36.6
N.A.
27.3
22
N.A.
34.5
Protein Similarity:
100
98.8
95.5
85.6
N.A.
36.7
81.2
N.A.
60.3
57.5
N.A.
47.5
N.A.
42.3
42.9
N.A.
47.9
P-Site Identity:
100
100
93.3
26.6
N.A.
20
26.6
N.A.
13.3
13.3
N.A.
46.6
N.A.
20
0
N.A.
0
P-Site Similarity:
100
100
93.3
33.3
N.A.
60
40
N.A.
26.6
20
N.A.
46.6
N.A.
33.3
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
23.6
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
40.9
N.A.
N.A.
39.4
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
0
0
15
29
15
8
0
15
22
15
15
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
50
22
15
0
15
8
0
0
15
15
8
8
8
% D
% Glu:
15
43
8
15
36
15
8
0
15
29
0
8
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
8
0
0
0
0
0
0
8
29
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
8
22
15
0
8
8
29
43
15
0
0
0
29
29
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
0
8
0
0
8
15
36
0
15
22
8
15
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
50
29
15
22
15
29
8
50
22
15
36
15
22
15
15
% S
% Thr:
8
0
0
8
8
0
8
0
8
0
8
8
43
29
8
% T
% Val:
0
0
0
8
8
8
0
8
0
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _